The meeting will focus on advances in our understanding the intricate roles and interactions of ROS, NAD, and GSH within the framework of redox biology, not only highlighting their importance in health and disease but also underscoring the potential of therapeutic interventions that aim to balance these crucial molecules. Such strategies hold the promise of preventing and treating a diverse array of diseases, particularly those associated with aging and oxidative stress. Key Sessions • Understand the generation, biological roles and dual nature of reactive oxygen species (ROS) in cellular signaling, gene expression and cell death.• Examine the protective mechanisms of antioxidants such as glutathione (GSH) in maintaining cellular redox homeostasis and preventing oxidative damage.• Determine the biosynthesis and function of nicotinamide adenine dinucleotide (NAD) in ATP production, DNA repair and stress responses. • Explore the contribution and therapeutic potential of oxidative stress to diseases like cancer and neurodegenerative disorders.• Assess strategies for enhancing NAD to treat age-associated diseases.