The primary goal of this conference is to bring together scientists, engineers and clinicians involved in the application of optics to biotechnology, medicine, and surgery. Clinical translation and technology commercialization are major areas of emphasis. By focusing on some of the most topical directions, this conference provides a forum for researchers of our field to access our most important progresses and to chart course for future research through formal and informal discussions. Through providing ample time for informal networking, the conference optimizes possible positive interactions among trainees, junior investigators, and established experts. This interaction is vital to cultivate the next generation of scientists and engineers in biomedical optics. The proposed conference will be a continuation of meetings on this topic sponsored by Engineering Conferences International for more than 22 years.