4th Immuno-Metabolic Mechanisms of Atherosclerosis Conference

Memo

Atherosclerosis and its complications remain the primary cause of death in the industrialized world and emerging economies worldwide. Dyslipidemia constitutes a significant risk factor for the development and progression of atherosclerotic lesions but may also lead to systemic disturbances - particularly metabolic dysfunction - that also influence cellular metabolism and function.  This meeting aims to provide attendees with a comprehensive overview of current research on atherosclerosis with a focus on the latest and most exciting developments in the immuno-metabolic mechanisms that govern disease initiation and progression. There is little doubt that the next most exciting therapy to combat cardiovascular disease will be based on targeting biological pathways that will have been discussed during this conference. Seven sessions are planned and will highlight the following major research areas: Cellular vessel wall and plaque diversity Cellular metabolism, cell death and immunity Transcriptional regulation in vascular cells Innate immunity and macrophage biology Adaptive immune mechanisms and autoimmunity Immunometabolism and leukocytes Lifestyle factors and vascular inflammation Multiomics and systems analyses  Human translational studies, drug development and clinical trials